Minocycline – Countering the Potential Side Effects


Today I’ve started minocycline, an antibiotic used for the treatment of skin issues. Tired of breaking out? I am. I am completely over it. I haven’t been a teenager in bloody years. Science, can you help out a little here?

Science says “Yes!” but only what the local GP can prescribe as a first-line (some literature says it’s a second-line) treatment. Now I’d done some reading before going into the GP and tetracycline antibiotics tend to develop resistance… so I naturally asked the doctor if there was any risk of resistance building to which he said no.

Well that rules this doctor out as being well educated. Seriously, what is taught at doctor school? I understand he is a general practitioner, but antibiotics should be pretty well understood… at least so I thought.

Anyway, while waiting for an appointment with a specialist, i.e. someone who can write a script for something that works more long-term I figured I’d give the old minocycline a shot. Why not, what else is there to do?

Figured I’d make a list of the what I’m doing to try and counter them and see if they do anything at all. This is a list of the things I’ll be trying, whether they work or not will be decided at a later date.

Vitamin A
Apparently, there is light evidence that vitamin A can cause intracranial pressure to increase.
I’ve switched my multivitamin to a non-vitamin A containing brand (Swisse).

Vitamin C
250mg at the same time as minocycline 50mg may reduce or counter any discolouration of teeth.

Lactobacillus survives digestion pretty well, which not all probitics can do. After a bit of “internet” research it has all boiled down to either Swisse or Ethical Nutrients – both refrigerated products.

Ethical Nutrients has Lactobacillus acidophilus (NCFM) plus Bifidobacterium animalis subsp. lactis (Bi-07). Swisse has Bifidobacterium animalis subsp. lactis (HN019), Bifidobacterium animalis subsp. lactis (Bi-04) and Lactobacillus acidophilus (La-14).

It should also be noted that genetically, NCFM and La-14 are 99.98% similar – a deletion here, genes affected there. The differences between Bi-04, Bi-07 and HN019 are also minor. Bi-04 and HN019 are stable in a freeze dried state. HN019, Bi-04 and Bi-07 on a genetic level are even more similar to each other than NCFM and La-14. Incredible!

Reduce from 100mg to 50mg after 15 days to reduce any side effects.

Three months on until symptoms return then begin again for three months.

Inevitably antibiotic resistance will set in and ruin everything. Then it is just a matter of switching to another solution like isotretinoin.

Ultimately though, I just need to give it time to see what happens. Stay tuned! 🙂

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